Biological effect of cigarette smoking in endothelial dysfunction: Study of biomarkers of endothelial function, oxidative stress, inflammation, and lipids

<b>Aims:</b> Tobacco use is involved in endothelial dysfunction, a key marker of cardiovascular diseases. The contribution tobacco their development assessed by dysfunction-related biomarkers smokers and non-smokers.<br /> <b>Methods:</b> 138 83 non-smokers were recruited. Parameters reflecting the function, lipid profile oxidative inflammatory status, quantified. Data used to determine ability differentiate <b>Results:</b> Elevation inflammation stress as well alteration function lipids observed. Two combinations, including one implying only routine parameters, identified allowed correctly classify >84% cases.<br <b>Conclusions:</b> Oxidative shown altered smokers, leading dysfunction. Endothelial terms discriminate from non-smokers. possibility discrimination based on classic parameters blood test appeared conceivable.